Barbara McClint. Biography

However, next year, concerned about the growth of Nazism, she returns to Cornell, where before G. realizing that she has little chance of further advancement, M. In the fall, she accepted the proposal to become an employee of the Carnegie Washington Institute in the Sold-Spring Haber, where he has been conducting his studies on corn genetics. In the winter months, she analyzes the results of experiments conducted by the previous summer, and plans to experiments for next year.

In the summer it grows corn on the site in front of the laboratory. Early experiments suggested her that there are mobile genetic elements in the chromosomes of corn. In the summer of G., noting a similar phenomenon in the cobs in grains, it comes to the conclusion that one of the subsidiaries of a specific genetic system in one of the subsidiaries, which the other plant does not possess.

This phenomenon is now called a genetic transposition, and genes included in the process - transposons, or migrating genes. The obtained experimental results gave M. to it two transposing genes were included: a dissociator named M. DS Genom, and activator-as-Gen. According to her observations, the genetic system worked as follows: if the DS-Gen moved to the chromosomal section next to the structural genome, for example, to the structural gene that controls the pattern of the strips on corn leaves, it served the phenotypic expression of the structural gene and the strip on the leaves.

However, the suppression provided by the structural genome was effective only if the al-Gen took a place near the other two genes. If the AS-Gen moved transposed to a more distant section, the suppression of the structural gene DS gen did not occur and the stripes on the leaves were bright. According to M., M. made, this discovery had far -reaching consequences: for example, using migrating genes, it was possible to explain how resistance to antibiotics is transmitted from one type of bacteria to another.

Model M. Scheme M. in G. Due to the fact that the hypothesis of mobile, transposing genes violated the dogma that existed in the genetics of genes as stable components of chromosomes, its materials did not attach serious significance, and also, perhaps, because the speaker was a woman. From in G. to the time when she resumed work on corn genetics and mobile genes, specialists in the field of bacterial genetics revealed regulatory genes in bacteria, reminiscent of those that M.

passed more than three decades from the moment the work was completed, which was now merit. In an interview with his biographer Evelyn Fox Keller M. And you forget about yourself. The main thing is what you forget about yourself. ” Confirming the characteristics of the members of the Nobel Committee, who called her a loner, M. She was never married. In addition to the Nobel Prize, M.

It has honorary degrees of Rochester University, Smith College, Missouri University, University of Yale, Williams College, New York University.